Revolutionary new HIV drugs are being made available in 120 low-income countries, but many important populations are being left out. Sophie Cousins reports.
But at a recent meeting about long COVID that we hosted, somebody reminded us that AZT [azidothymidine] was originally developed as a chemotherapeutic for cancer [in 1964] and was sitting on a ...
The most successful of the anti-HIV agents discovered in this early period, and also the first to be licensed for clinical use, was azidothymidine (AZT), which emerged from a screening effort of ...
We can provoke the accumulation of replication gaps by treatment with the chain-terminating drug, azidothymidine—we have identified and are studying several new repair factors that promote tolerance ...
The first anti-leukaemia drug was developed from two chemicals found in this sponge. These chemicals are also part of the breakthrough drug azidothymidine (AZT), which was first administered in the ...
Gino only got sicker. He developed Kaposi's sarcoma and had bad side-effects from azidothymidine (AZT), an antiretroviral medication used by Aids patients at the time. Life on London's first Aids ...
Some pyrimidine analogs, such as azidothymidine (AZT) and stavudine (d4T), are used as antiviral drugs to treat HIV/AIDS. These drugs work by inhibiting the viral reverse transcriptase enzyme, ...
Patients with HIV infection are at an increased risk of a number of malignancies, including Kaposi's sarcoma (KS) and certain B-cell lymphomas. Most of these tumors are caused by oncogenic DNA ...