Exocytosis is the process by which cytoplasmic secretory vesicles fuse with the cellular membrane, releasing contents to the extracellular space. The extrusion of large extracellular vesicles is ...
CA inhibition abrogates lysosomal acidification and causes tau secretion by lysosomal exocytosis without having a prion effect. This mechanism lowers intracellular tau and is neuroprotective in ...
Carbonic anhydrase inhibitors show potential in reducing tau protein buildup, offering new therapeutic avenues for neurodegenerative diseases like tauopathies.
Protein contact dermatitis is an allergic skin reaction induced principally by proteins of either animal or plant origin. The clinical presentation is that of a chronic dermatitis, and it is often ...
A preclinical University of Toronto study is revealing new insights into the molecular machinery that drives the aggressiveness of pancreatic cancer. This cancer’s ability to invade and spread to ...
Dietary protein absorption in neonatal mammals and fishes relies on the function of a specialized and conserved population of highly absorptive lysosome rich enterocytes (LREs). The gut microbiome has ...
What’s the correct Horus Heresy book order? This guide provides the full Horus Heresy reading order for all the novels, and the Siege of Terra mini-series, complete with spoiler-free summaries for ...
One well-studied route of EMV production is through multivesicular body (MVB) exocytosis, in which, fusion of the limiting membrane of MVBs with the cell plasma membrane results in release of their ...