Engineers have cooked up a new way to improve mRNA delivery, developing an optimal 'recipe' for ionizable lipids -- key ingredients in lipid nanoparticles (LNPs), the molecules behind the COVID-19 ...
Yeast Yra1 and its metazoan orthologues bind mRNAs and interact with multiple mRNA export factors.Transport of proteins and small RNAs does not require Yra1 or any other proteins required for mRNA ...
a technique used in both chemistry and biology that mimics the process of natural selection, the researchers combined precision with rapid output to achieve their ideal lipid "recipe." The process ...
Further advances in mRNA biology, delivery, and manufacturing will pave the way for the development of a raft of novel mRNA-based vaccines and therapeutics in the near future. Dr Wiklund is ...
Some of the newly discovered interactions with messenger RNA (mRNA) facilitate protein secretion ... Wilson Distinguished Service Professor of Chemistry and Professor of Biochemistry and Molecular ...