The collaboration aims to identify a small molecule that targets mutant androgen receptor (AR) mRNA splicing and causes selective destruction of the disease-causing mRNA. By modulating mRNA splicing, ...

Scientists from the University of Pennsylvania have developed an ideal “recipe” for ionizable lipids, which are essential ...

To enhance mRNA distribution, Penn engineers have created an ideal “recipe” for ionizable lipids, which are essential ...

RNA therapeutics promise rapid, personalized and flexible treatments against multiple diseases. In this article, we will ...

Researchers recently developed a new approach for identifying new cellular RNA targets of snoRNAs. They uncovered thousands of previously unknown targets for snoRNAs in human cells and mouse brain ...

Engineers have cooked up a new way to improve mRNA delivery, developing an optimal 'recipe' for ionizable lipids -- key ingredients in lipid nanoparticles (LNPs), the molecules behind the COVID-19 ...

A new approach for identifying new cellular RNA targets of snoRNAs uncovered thousands of previously unknown targets ...

Penn Engineers have cooked up a new way to improve mRNA delivery, developing an optimal “recipe” for ionizable lipids — key ...

Penn Engineers have cooked up a new way to improve mRNA delivery, developing an optimal "recipe" for ionizable lipids—key ...

Scientists have discovered that tRNAs can determine how long mRNAs exist in a cell, causing some messages to be stabilized ...

University of Chicago scientists have expanded our understanding of snoRNAs, discovering their extensive influence on ...

Researchers have cooked up a new way to improve mRNA delivery, developing an optimal “recipe” for ionizable lipids — key ...