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eLife
6 天
Mechanistic target of rapamycin (mTOR) pathway in Sertoli cells regulates age-dependent ...
For the first time, a molecular mechanism is identified, for experimental acceleration and deceleration (rejuvenation) of sperm epigenetic aging.
9 小时
赛诺根:衰老干预技术突破 为实现延缓衰老提供解决方案
衰老干预技术领域取得的突破,为实现延缓衰老提供了解决方案。据中华医学会老年医学会发布的《延缓衰老药物干预研究中国老年医学专家共识 (2024)》显示,目前有前景的延缓衰老策略包括适度降低营养物感应网络活性、降低雷帕霉素蛋白复合物1 (mTORC1)的活性、去除衰老细胞、利用身体的内源代谢物重新焕发干细胞活力以及优化机体微生物组等。
SciTech Daily
6 天
New Research Reveals That Cannabis Can Reverse Brain Aging
Long-term, low-dose cannabis treatment has been shown to reverse brain aging and enhance cognitive abilities in mice by ...
BMJ
4 天
mTOR inhibition by metformin impacts monosodium urate crystal–induced inflammation and ...
Recently, it was shown that MSU crystals can induce mechanistic target of rapamycin (mTOR) signalling in monocytes encountering these crystals in vitro. The mTOR pathway is strongly implicated in ...
oncnursingnews
2 天
NKT2152 Shows Promising Efficacy in Advanced Clear Cell Kidney Cancer
NKT2152, a novel HIF2a inhibitor, demonstrates significant efficacy in patients with advanced clear cell renal cell carcinoma ...
人民资讯 on MSN
8 小时
产业新观察|赛诺根:干预技术是关键岗位的重要保障
“衰老干预是当前生命科学前沿研究的热点,进入21世纪,以麻省理工学院、哈佛医学院、梅奥诊所为首的科研学术机构先后取得了一系列重大突破,出现了mTOR通路抑制、细胞自噬和线粒体自噬激活、衰老细胞靶向清除(希诺裂)等前沿技术,这些技术在延长健康寿命、维持 ...
Healthline
6 天
Type 2 Diabetes Drug Metformin May Help Reduce Viral Reservoir in People with HIV
Metformin, a common medication used to treat type 2 diabetes, may also help reduce the viral reservoir in people living with ...
News Medical
2 天
How Does Semaglutide Work to Lose Weight?
Semaglutide injections effectively support weight loss by regulating appetite and glucose levels, offering benefits for ...
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