Expert Rev Anticancer Ther. 2009;9(4):511-523. As the name implies, mTOR is inhibited by rapamycin. Rapamycin (also known as Sirolimus or Rapamune ®) is a macrocyclic lactone antibiotic that was ...
In this study, we discover that DYRK1A interacts with TSC1 and TSC2. We show that DYRK1A phosphorylates TSC2 at T1462 and, therefore, is a possible positive regulator of mTORC1 activity and cell ...
In August, the Brigham Young University football team organized a Zoom call with BYU–Pathway Worldwide students in Africa. The Cougars were thrilled when hundreds joined the call. Technology limited ...
In fact, Wilkinson hopes an agreement between the Pathways Alliance consortium, Ottawa and Alberta can soon be reached to get one of the world’s largest carbon capture networks moving ...
Tumor-associated macrophages (TAMs) also store glycogen and can perform glyconeogenesis. Finally, macrophage glycogenolysis and the pentose phosphate pathway (PPP) support cytokine secretion and ...
“Therefore, I think it is important for us to then think … how do we create a lot more choices, a lot more flexible pathways to cater to the needs of the different students and also to meet ...
The proposed pathway would cross through the VIA Rail station property. However, staff say it's pausing the EA study because VIA Rail's future redevelopment plans for the site are unknown.
Western blot assays revealed MCT inhibited the phosphorylation levels of the PI3K/AKT/mTOR pathway. To elucidate the role of autophagy in mediating MCT-induced apoptosis, we further pretreated PRHs ...