近日,广东省人民医院鲁冰、赵蔚团队在《Nature Cancer》上发表了题为“Phase separation of phospho-HDAC6 drives aberrant chromatin architecture in triple-negative breast cancer”的文章。该论文首次揭示了三阴性乳腺癌(TNBC)中存在磷酸化HDAC6蛋白形成的凝聚体,并提出了通过干预磷酸 ...
Application Fluorescent confocal image of HepG2 cells stained with phospho-GATA6-Y271 antibody. HepG2 cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.2%, 30 min). Cells were ...
Zhang's team utilized the rapid phospho-shift of OsCTR2, a negative regulator of rice ethylene signaling, in response to ethylene as a sensitive readout for signal activation. Analysis of an ...