目前，我们对肾病的发生发展，特别是细胞和分子层面的认识并不明确。因此，许多肾病患者依然会发展为终末期肾脏病（ESRD），其中我们对糖尿病肾病（DKD）的认识也不是特别明确。特别是为什么有些糖尿病患者终身不发生DKD，而有些在确诊糖尿病时，就已经出现了 ...

The glomerular filtration barrier, from the blood to the urinary space, consists of endothelial cells, a basement membrane and specialized epithelial cells called podocytes. Endothelial cells have ...

IgA nephropathy is an autoimmune kidney disease, and complement, a component of the innate immune system, plays a role in the condition's pathogenesis.

IgA nephropathy is an autoimmune kidney disease, and complement, a component of the innate immune system, plays a role in the ...

A specialized low-salt fasting-mimicking diet revives kidney function in preclinical animal models and patients with chronic ...

Moin Saleem and colleagues at the University of Bristol. Long-term, single payment licensing model Discounted rates for SMEs Available under MTA for academic use. Podocytes are highly specialised, ...

Purespring’s gene therapy, PS-002, uses a viral vector to target kidney cells—known as podocytes—to treat IgA nephropathy, a ...

Podocytes play a pivotal role in regulating glomerular function, the filtering process that removes waste and excess water ...

A study reveals that a low-salt fasting-mimicking diet slows kidney disease progression in animal models and shows protective ...

IgA nephropathy is an autoimmune kidney disease, and complement, a component of the innate immune system, plays a role in the ...

Data were also presented supporting a growing body of evidence that LUPKYNIS through unique mechanism of action, favorably ...