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Cancer Cell:新研究揭示抗CSF-1R治疗的纤维化反应促进胶质母细胞瘤的复发
Joyce实验室已证实CSF-1R抑制能将这些免疫细胞重新编程为抗肿瘤状态,从而诱导肿瘤显著消退。然而,正如Science期刊报道的那样,大约一半的小鼠在对这种疗法产生初步反应后出现复发。Joyce说,“最引人注目的是,每次脑瘤在接受免疫疗法后复发, ...
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