POLK expression in neurons and report an important observation that POLK exhibits an age-dependent change in subcellular localization, from the nucleus in young tissue to the cytoplasm in old tissue.

Department of Radiation Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China ...

In SNALPs, the backbone-modified siRNA is encapsulated within a closed shell of a cationic-zwitterionic lipid bilayer, furnished with an outer PEG shield (Figure 2A). The lipid bilayer contains a ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Senescent cells present an excessive flux of ...

为了预测BDE-47的结合位点和蛋白质结构，进行了分子对接。经过这一筛选步骤后，还剩下6个基因。对接结果显示，AOX1、PIK3R1、FGF2、CAV2、CYP2E1和TOP2A的对接得分相对较高，BDE-47通过H键与这些蛋白残基紧密结合（图5A- ...

NHC Key Laboratory of Carcinogenesis and Hunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, ...

Ottawa Institute of Systems Biology, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada Department of Biochemistry Microbiology and Immunology, Faculty of Medicine, University of ...