Their analysis identified two key dysregulated pathways: GRN-SORT1 axis in TREM2 macrophages and the IL-13-IL-13RA1 axis in keratinocytes, both consistently upregulated in acne lesions.
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Acne, psoriasis, chickenpox, and other conditions may cause skin lesions. Seek medical attention if you have a rash or an infection or your lesions resemble those caused by MRSA or cellulitis.
The inclusion criteria for the study were as follows: age >12 years, 30-100 noninflammatory acne lesions, 20-50 inflammatory acne lesions, and no nodules or cysts. Investigators assessed treatment ...
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“It also plays a role in the healing of skin lesions and can reduce the severity of acne,” she continues, noting that low levels have been linked to more severe acne. Vitamin A is a key ...
Isotretinoin is highly effective in clearing acne lesions (by 85% in one study after four months of use). Only around one-quarter of patients who use it require a second course of treatment.