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The underlying mechanisms of loss of distal capillary endothelial cells (ECs) and obliterative vascular lesion formation remain unclear. Method and Results: Our recent single-cell RNA sequencing, ...

Background: Understanding the intricate dynamics of lung microcirculation and capillary endothelial cells (ECs) is crucial for shedding light on both normal physiological processes and the ...

The capillary blocks mainly involved red blood cells and not immune cells, suggesting that the microvascular complications in type 1 diabetes may arise more from endothelial dysfunction than from ...

Although the pathophysiology of mesangial cells has long been considered to be the major factor in the development of glomerulosclerosis in type 1 or type 2 diabetes, more recent evidence suggests ...

The authors also surveyed cognate receptors expressed in epithelial cells, endothelial cells, stromal cells, immune cells, and pulmonary sensory neurons, identifying potential local targets for the ...

Here, we demonstrate that induced endothelial-specific depletion of the transcription ... In the body, thread-like blood vessels called capillaries weave their way through our tissues to deliver ...