New research from reveals that the gut microbiome regulates the body’s diurnal (day-night) rhythms in stress hormones. Depletion of gut microbiota results in disruptions in the brain’s core circadian ...
Elobixibat acts by inhibiting the reabsorption of bile acids from ileum, thus increasing their concentration in the colonic lumen, leading to increased bowel movements due to stimulation of both ...
Such effects could lead to increased digestive enzymes and bile secretion, all of which support a healthy gastrointestinal (GI) tract. None of these effects has been proven in humans. Other research ...
Department of Chemical Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, United States Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania ...
Introduction: TGR5 belongs to G-protein coupled receptor family, that mediates bile acid signaling. Activation of TGR5 by bile acids triggers intestinal glucagon-like peptide-1 secretion, whereby ...