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在单细胞大脑图谱中追踪阿尔茨海默氏症的早期轨迹
神经胶质细胞的炎症和某些抑制细胞的丧失可能在诊断前几十年就开始了疾病级联。 阿尔茨海默病诊断的认知能力下降就像熊熊大火的烟雾:当它显现出来的时候,损害已经开始了。这种损害包括β -淀粉样蛋白斑块和tau蛋白缠结的积累,它们会杀死海马体、内 ...
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