The centrosome has been a subject of fascination for cell biologists for at least a century. It is at the centre of the cell and is the structure on which microtubules organize themselves both ...
For almost a century, our understanding of the tiny structure at the centre of the cell called the centrosome was limited to its ability to organize mitotic spindles and other microtubule arrays.
Breslow and his colleagues observed that PPP2R3C gathered at centrosomes of typical, healthy cells, supporting the idea that ...
However, if this process fails, results can be catastrophic. The resulting cells, locked together like Siamese twins, would ...
As the centrioles move toward the poles of the cell, they create a region of cytoskeletal production called the centrosome. Be mindful of the vocabulary you introduce to your students. The long ...
Just before division, two complex protein structures, known as centrosomes, emerge, forming two opposing poles in the mother cell. These centrosomes grow long protein filaments, the spindle ...
The goal of my research is to understand the biogenesis of centrioles/centrosomes and primary cilia, and how defects in these processes affect mammalian cell physiology and evoke stress responses.