Scientists have developed a method to improve the stability and efficiency of organic light-emitting diodes (OLEDs), a ...

More information: Suman Kuila et al, Rigid and planar π-conjugated molecules leading to long-lived intramolecular charge-transfer states exhibiting thermally activated delayed fluorescence ...

However, the twisted conformation in TADF molecules limits device lifetimes. While rigid molecules enhance stability, their planar, π-conjugated structures hinder ICT, making it challenging to improve ...

Twenty-four fragments (44%) were conjugated to additional functional molecules, such as radioisotopes or cytotoxins. These immunoconjugate candidates were all studied as anticancer agents ...

Quantitative Biology Research Group, Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji-cho, Okazaki, Aichi 444-8787, ...

These new molecules significantly shift the understanding ... molecular bonding patterns to the disruption of molecular pi-conjugation in the excited state, helping explain this unprecedented ...

Antibody-drug conjugates (ADCs) represent a promising cancer treatment modality designed to deliver highly potent cytotoxic ...

When you look in a mirror, the reflection is fundamentally you, but with a perfect reversal of all your features. This illustrates a phenomenon we also see in the tiny world of molecules.

Manufacturing practices are evolving to advance antibody drug conjugates (ADCs) for cancer treatment through a targeted ...

Synthesis can also include functionalization by conjugation to bioactive molecules. The low-cost synthesis of high-quality MXenes is crucial for applications, yet challenges remain. The authors ...

This paper presents the important discovery that lipid metabolic imbalance caused by Snail, an EMT-related transcription factor, contributes to the acquisition of chemoresistance in cancer cells.

Dec. 5, 2024 — The Horner--Wadsworth--Emmons (HWE) reaction is commonly used in organic chemistry to synthesize conjugated aldehydes. However, traditional HWE reaction methods sometimes have ...