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Cell Genomics:结合孟德尔随机化与AlphaFold3发现阿尔茨海默病蛋白标志 ...
综上所述,该研究展示了如何通过整合基因组和蛋白组学数据、因果推断与先进人工智能蛋白质三维结构预测工具,填补该领域的关键空白,为阿尔茨海默病的下一代研究奠定了坚实基础。通过识别蛋白标志物的三维结构变化,促进了对疾病关键通路的靶向干预研究,为精准医学带来 ...
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