Carbonic anhydrase inhibitors show potential in reducing tau protein buildup, offering new therapeutic avenues for neurodegenerative diseases like tauopathies.

CA inhibition abrogates lysosomal acidification and causes tau secretion by lysosomal exocytosis without having a prion effect. This mechanism lowers intracellular tau and is neuroprotective in ...

Environmental pollution is a major health problem that affects the health of individuals worldwide and is cumulative with ...

In recent years, peptides have emerged as critical players in various fields of biological and molecular research. Among ...

Exocytosis is the process by which cytoplasmic secretory vesicles fuse with the cellular membrane, releasing contents to the extracellular space. The extrusion of large extracellular vesicles is ...

This important paper demonstrates that different PKA subtypes exhibit distinct subcellular localization at rest in CA1 neurons. The authors provide compelling evidence that when all tested PKA ...