Gout patients frequently have a number of comorbidities, including obesity, hypertension, high serum lipid and cholesterol levels, kidney disease, diabetes, and cardiovascular disease. [2,7,19 ...

The impairment of HRQOL in patients with gout increases with the presence of tophi and the frequency of flares, even after adjusting for covariates. Gout symptoms are also associated with greater ...

Chronic tophaceous gout is characterized by tophi, an accumulation of urate crystals ... nerve compression can also lead to ...

Tophi are firm, painless yellow lesions that form in and around the joints in people with advanced gout. They have a uric ...

He had been treated for several years with colchicine for gout. On entry he was semistuporous and had a left hemiplegia. There was a tophus on the left ear and 1.5-cm. bunion-like masses over the ...

and chronic gouty arthritis with multiple gouty tophi. He had also had hyperuricemia for many years, with uric acid concentrations of up to 9.8 mg/dl. Initial treatment with febuxostat 80 mg bid ...

Severe gout was defined by the presence of 5 or more tophi. The mechanisms of generalized neuropathy remain unclear and likely involve multiple factors. Patients with gout and neuropathic symptoms ...

crystals form and collect in your joints and cause gout. Uric acid buildup also can lead to disfiguring lumps called tophi that form around the affected joint. And if the crystals accumulate in ...

Gout affects around 9 million Americans, and around 50% of those with gout will have their first attacks begin in the big toe. The severity of gout will depend on the individual, but, on average ...

Gout was once seen as a “rich man’s disease” and King Henry VIII was a famous sufferer. However, it can affect anyone, and in recent years the number of cases of gout has been on the ...

Regularly cleaning your drains can help prevent clogs, slow drainage, foul odors and a host of other potential issues. But with so many drain cleaners on the market, picking an efficient and safe ...