Her general practitioner diagnosed gouty arthritis because of a high serum uric-acid level (600 µmol/l; normal range 270–380 µmol/l) coexistent with tophi in her hands, and initiated ...

Chronic tophaceous gout is characterized by tophi, an accumulation of urate crystals ... nerve compression can also lead to ...

The present study quantifies the impact of the presence of tophi and frequency of acute gout attacks on health-related quality of life (HRQOL), productivity, and healthcare resource utilization.

In some individuals, particularly the elderly, gout episodes become chronic, and crystals of uric acid metabolism byproducts are deposited over the affected joint, forming swellings known as tophi.