Desire to identify antigen-specific T cells through the MHC/peptide complex was always there ... Viruses (Human Immunodeficiency Virus-Acquired Immunodeficiency Syndrome, Epstein Barr ...
T cells are white blood cells that are important for adaptive immunity. They have unique cell surface receptors that are generated by randomly assorting genes. These receptors allow T cells to ...
Figure 3: Antibodies against SSc and viral peptides induce apoptosis of endothelial cells. A direct link between autoantibodies, HCMV infection and endothelial cell damage in SSc is still lacking.
Expansion of antigen-specific T cells (cytomegalovirus) counts for reduced repertoire diversity. B-cell functions are altered with age: antibody production, affinity and isotype switching.
Expansion of antigen-specific T cells (cytomegalovirus) counts for reduced repertoire diversity. B-cell functions are altered with age: antibody production, affinity and isotype switching.
These therapeutic T cells zero in on specific protein targets known as antigens ... He was the principal investigator on the first human trial of transferred therapeutic T cells, to prevent dangerous ...
Greenberg’s findings initially led to approaches to protect immune-compromised patients from cytomegalovirus infections and to enhance control of ... Protocol 2498: Phase I/II Study of Adoptive ...
I started my research career with a doctorate in the Weatherall Institute of Molecular Oxford supervised by Professor Andrew McMichael, studying the role of HIV-specific cytotoxic T lymphocytes (CTL .