Groundbreaking bone marrow transplant saves 10-month-old boy with rare genetic immunodeficiency, funded by The Hans ...

Expansion of antigen-specific T cells (cytomegalovirus) counts for reduced repertoire diversity. B-cell functions are altered with age: antibody production, affinity and isotype switching.

Continuing their journey to develop a vaccine for HIV, Oregon Health & Science University researchers have identified a gene ...

The interactions between OX40 ligand (OX40L) and OX40, 4-1BBL and 4-1BB, CD70 and CD27, and TL1A and death receptor 3 (DR3), positively regulate T-cell responses ... that are specific for TNF ...

New preclinical data demonstrates that CMV antigens identified with Evaxion’s AI-Immunology™ platform trigger targeted immune responses Results ...

While V genes, being more diverse, contribute to a broad scope of antigen recognition, the J genes, being less diverse, could be more specific to certain antigenic epitopes. TCRclub proves to be a ...

Human CMV gene blocks necessary T cell response; HIV vaccines engineered without the gene being tested in clinical trials ...

1Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut. 2Department of Genetics, Yale University School of Medicine, New Haven, Connecticut.