DNA methylation is the covalent addition of methyl groups to DNA bases, typically the cytosine of CpG dinucleotides. It is catalyzed by methyltransferase enzymes using a S-adenosyl methionine ...
However, it has shown limitations in terms of high costs and inefficiencies. The productivity and accuracy of DNA methylation detection rely critically on the optimization of methodologies and the ...
Alterations in lipid metabolism and DNA methylation are 2 hallmarks of aging. Connecting metabolomic, epigenomic, and aging outcomes help unravel the complex mechanisms underlying aging. We aimed to ...