Phosphorylation is the enzymatic process through which a phosphate group is added via an ester bond, generally by a kinase, to either a small molecule or a protein. Protein phosphorylation is ...

Defects in the oxidative phosphorylation (OXPHOS) system — the final biochemical pathway in the production of ATP — result in devastating, mainly multisystem diseases. The OXPHOS system is ...

Herein, we reconstitute FRQ and the FFC to assess the global and site-specific structural properties of these moieties, as well as the dependence of their properties on multisite phosphorylation. FRQ ...

Despite an increase in glycolysis, however, here we show that non-transformed mouse fibroblasts also increase oxidative phosphorylation (OXPHOS) by nearly two-fold and mitochondrial coupling ...