SPONTANEOUS hypoglycemia in infancy may, on rare occasions, be precipitated by the ingestion of casein, L-leucine or isovaleric acid, an intermediary metabolite of leucine. 1–4 Recently ...

The study highlighted glucocorticoid-induced leucine zipper (GILZ), a protein central to glucocorticoids’ anti-inflammatory effects but without their adverse outcomes, as a potential game-changer.

An AlphaFold-predicted of human NRL model is shown, with protein domains highlighted. MTD = minimal transactivation domain, EHD = extended homology domain, BM = basic domain, bZIP = basic leucine ...

It involved the activation of DLK, or dual leucine zipper kinase, which subsequently activated pathways related to cellular stress and injury. Inhibiting DLK with a drug or genetic techniques was ...