Lipids Open the Door. Microglial cells treated with unlipidated (top) or lipidated (bottom) ApoE (yellow) along with fluorescently tagged Aβ (green). Lipidated ApoE was more readily internalized and ...

Dietary protein absorption in neonatal mammals and fishes relies on the function of a specialized and conserved population of highly absorptive lysosome rich enterocytes (LREs). The gut microbiome has ...

A complex organ such as the kidney presents many difficulties in the determination of success of preservation, as failure in one system of organ function may compromise the physiological ...

Think back to that basic biology class you took in high school. You probably learned about organelles, those little “organs” ...

More information: Shane K. B. Taylor et al, The neurotrophic factor MANF regulates autophagy and lysosome function to promote proteostasis in Caenorhabditis elegans, Proceedings of the National ...

Researchers have discovered a previously unknown cell-protecting function of a protein ... MANF was present in structures known as lysosomes which are associated with lifespan and protein ...

Libra Therapeutics, Inc., ("Libra") a private biotech developing novel therapeutics to restore cellular balance and attenuate neurodegeneration, today announced the appointment of Shawn A. Scranton, ...