This review explores the role of lysosomal stress in pancreatic diseases, particularly diabetes mellitus. Lysosomes, crucial ...

The discovery of lysosomes led to many new questions. The most critical question was: what was the physiological function of this "bag" of enzymes? The Function of Lysosomes One of the definitive ...

The Golgi apparatus functions as a molecular assembly line ... they are directed to their appropriate destinations — either lysosomes, storage vesicles, or the plasma membrane (Figure 2).

Think back to that basic biology class you took in high school. You probably learned about organelles, those little "organs" ...

More information: Shane K. B. Taylor et al, The neurotrophic factor MANF regulates autophagy and lysosome function to promote ...

Within these tissues, MANF was present in structures known as lysosomes which are associated ... helping them function better for longer. “Although our research focused on worms, the findings ...

Stress granules (SGs) form in response to diverse environmental signals. Here, the signaling pathways that connect lysosomal ...

The lab also studies mechanisms that regulate autophagy protein and lysosome function in endocytic trafficking and nutrient homeostasis. Figure 1. Entosis promotes cell competition. (A) Entosis ...

The lab also studies mechanisms that regulate autophagy protein and lysosome function in endocytic trafficking and nutrient homeostasis. Cell biologist Michael Overholtzer explores genes that make ...

Researchers have discovered a previously unknown cell-protecting function of a protein ... MANF was present in structures known as lysosomes which are associated with lifespan and protein ...