The discovery of lysosomes led to many new questions. The most critical question was: what was the physiological function of this "bag" of enzymes? The Function of Lysosomes One of the definitive ...

This review explores the role of lysosomal stress in pancreatic diseases, particularly diabetes mellitus. Lysosomes, crucial ...

The Lysosome This small particle acts as the digestive tract of the living cell. Its enzymes dissolve the substances ingested by the cell and under certain circumstances can dissolve the cell itself ...

Think back to that basic biology class you took in high school. You probably learned about organelles, those little "organs" ...

Dietary protein absorption in neonatal mammals and fishes relies on the function of a specialized and conserved population of highly absorptive lysosome rich enterocytes (LREs). The gut microbiome has ...

The lab also studies mechanisms that regulate autophagy protein and lysosome function in endocytic trafficking and nutrient homeostasis. Figure 1. Entosis promotes cell competition. (A) Entosis ...

The lab also studies mechanisms that regulate autophagy protein and lysosome function in endocytic trafficking and nutrient homeostasis. Cell biologist Michael Overholtzer explores genes that make ...

More information: Shane K. B. Taylor et al, The neurotrophic factor MANF regulates autophagy and lysosome function to promote proteostasis in Caenorhabditis elegans, Proceedings of the National ...

前言糖尿病和肝脏病是我国常见的慢性病，二者在发病机制、临床表现、诊疗靶点等多方面存在着相互作用或互为危险因素，共同管理有利于减轻疾病负担。为助力我国糖尿病肝脏病共管事业发展，本刊携手CHESS肝脏健康联盟共同推出“糖肝共管”文献月评专栏，每月分享有关 ...

In economics, the utility function measures the welfare or satisfaction of a consumer as a function of the consumption of real goods, such as food or clothing. Utility function is widely used in ...

Filled with digestive enzymes, lysosomes function as the cell's stomach and break down proteins, lipids, and other nutrients ...