Liver diseases, both acute and chronic, continue to pose significant clinical challenges due to high morbidity and mortality ...

Upon binding, these receptors initiate pro-inflammatory signaling pathways such as the NF-κB and mitogen-activated protein ...

Targeted therapy revolutionized cancer treatment, with gene fusions leading the way when the FDA approved imatinib in 2001 to ...

Researchers conducted a study to determine if variations in the MTNR1A gene, specifically the MRNR1A variant (rs374152717), could be a genetic cause of idiopathic osteoporosis.

Verastem Oncology submits NDA to US FDA for avutometinib plus defactinib to treat recurrent KRAS mutant low-grade serous ovarian cancer: Boston Monday, November 4, 2024, 14:00 Hrs ...

Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with cancer, ...

A cutting-edge study offers fresh insights into how roses defend themselves against the damaging fungus Botrytis cinerea, which causes severe losses in ornamental plants.

To analyze the clinical significance of Toll-Like Receptor 7/Interleukin-23/Interleukin-17 (TLR7/IL-23/IL-17) signaling pathway in patients with Acute Respiratory ...

However, whether T. chebula might serve as a safe, effective treatment for mild cognitive impairment (MCI) has not been sufficiently studied. As an early step, a research team has conducted a ...

These findings suggest potential pathways for targeted therapies in KRAS ... Fey et al, KRAS Loss of Heterozygosity Promotes MAPK-Dependent Pancreatic Ductal Adenocarcinoma Initiation and Induces ...

Schematic models of the core of MAPK/ERK pathway and human eIF3 complex. (A) The MAPK/ERK pathway activation by growth factors and receptor tyrosine kinases (RTKs). RTKs signal through GRB2-Sos and ...