Matchpoint Therapeutics Inc. has synthesized new diazepino-thieno-quinoxaline compounds acting as MAP kinase-activated protein kinase 2 (MAPKAPK2; MK2) inhibitors reported to be useful for the ...

Clinical-stage biopharmaceutical company Poolbeg Pharma announced on Wednesday that it has been granted a US patent for its ...

Sanofi SA has synthesized pyridoimidazolone compounds acting as mitogen-activated protein kinase 7 (MAPK7; ERK5) inhibitors potentially useful for the treatment of cancer.

X-ray crystallographic approaches combined with functional assays are used to address the hypothesis that bound water participates in the osmosensing mechanism as an allosteric kinase inhibitor. The ...

Janus kinase (JAK) inhibitors are a group of medications that can treat various types of arthritis, including rheumatoid arthritis (RA), cancer, dermatological conditions like atopic dermatitis and ...

Poolbeg Pharma (AIM: POLB, ‘Poolbeg’ or the ‘Company’), a clinical-stage biopharmaceutical company focused on the development and commercialisation of innovative medicines targeting diseases with a ...

(Alliance News) - Poolbeg Pharma PLC on Wednesday announced its immunomodulator I patent has been granted in the US. The London-based clinical stage biopharmaceutical company targeting diseases with a ...

Cordycepin, derived from fungi, shows promise in cancer therapy by inhibiting growth factor signaling pathways critical for ...

To dissect pathways mediating differentiation and LL-37 expression, specific inhibitors were applied. Inhibition of the protein kinase MEK enhanced butyrate induced AP activity while LL-37 expression ...