Inhibition of CDK6 may prevent arteriovenous malformations in hereditary hemorrhagic telangiectasia by regulating endothelial ...

Kangbaida (Sichuan) Biotechnology Co. Ltd. has disclosed proteolysis targeting chimeras (PROTACs) comprising a cereblon (CRBN) ligand coupled to a mitogen-activated protein kinase kinase kinase kinase ...

One possibility is that in an attempt to overcome the inhibition within the metabolic insulin-signaling pathway, hyperinsulinemia may continue to stimulate the mitogenic insulin-signaling pathway ...

Their findings, which were published in Science Advances, also offer new insights into 2'3'-cGAMP's role in cell migration and how the newly identified 2'3'-cGAMP/Rab18/FosB signaling pathway ...

If the FDA grants priority review, a decision on the NDA could come within six months after the 60-day filing period.

Here’s how it works. Should you get your directions from Google Maps or Apple Maps? It's a decision all iPhone users have to make at some point — regardless of whether you're a long-time ...

Google Maps and Waze have a lot of things in common, which makes sense considering Google is responsible for them both. But no matter how many updates happen, and how small the gap becomes ...

Mapping cell types in MS lesions reveals unique tissue niches and interactions, offering insights into the molecular drivers of multiple sclerosis progression.

However, this doesn’t have to be the case for your business. By building strong career pathways and offering meaningful training programs, you can retain top talent and help them thrive within ...

Palmitate disrupts hypothalamic function in GnRH neurons by regulating spexin (SPX) and its receptors, galanin receptor 2 (GALR2) and galanin receptor 3 (GALR3), through pathways involving protein ...

Single-cell analysis of CML patients bone marrow at diagnosis reveals coexistence of CD26-CD35+ healthy stem cells and CD26+CD35- CML stem cells, and how the ratio between these impacts TKI response.