Figure 1: Immunocytochemical detection of activation of MAP kinase and PI3 kinase pathways. Figure 3: NT3-induced potentiation of SSCs at NMJ requires activation of PI3 kinase and PLC-γ ...

CaMKII activates the HRI/eIF2α signaling pathway and inhibits the proteotoxicity induced by proteasome inhibition through ...

The authors present a valuable study exploring the interaction between JNK signaling and high sucrose feeding. The strength of evidence supporting these observations is solid, including multi-tissue ...

This manuscript describes the impact of modulating signaling by a key regulatory enzyme, Dual Leucine Zipper Kinase (DLK), on hippocampal neurons. The results are interesting and will be important for ...

One possibility is that in an attempt to overcome the inhibition within the metabolic insulin-signaling pathway, hyperinsulinemia may continue to stimulate the mitogenic insulin-signaling pathway ...

With over 15 years of experience in kinase drug discovery, DiscoverX offers the largest collection of nearly 500 biochemical and cell-based kinase assays. KINOMEscan® technology, our novel kinase ...

Is Google Maps not working? The app is fairly reliable, but it’s not impossible to run into an issue on occasion. Of course, it’s never fun when technology isn’t performing as intended ...

For example, in plants, specific metabolic pathways can produce glucose and chlorophyll. Metabolic pathways can be described as a series of chemical reactions that start with a substrate and ...

Dr. Ma adds, "Our results show that BB1 prevented the TNF-α increase in intestinal tight junction permeability via a toll-like receptor (TLR)-2 signal transduction pathway inhibition of NF-kB p50 ...

The inhibition of ERK5 is a potential complementary strategy for countering FAK inhibitor resistance in patients with lung ...

The biggest stories of the day delivered to your inbox.