Recent data suggests a direct link between the surface estrogen receptor and the mitogen-activated protein (MAP) kinase signaling cascade. MAP kinases are a family of serine–threonine kinases ...

Upon binding, these receptors initiate pro-inflammatory signaling pathways such as the NF-κB and mitogen-activated protein ...

In the study, "Melatonin receptor 1A variants as genetic cause ... calcium signaling, and mitogen-activated protein kinase pathways, which triggered osteoblast senescence and bone loss.

Fructose, the most common food sweetener, is widely used in processed sugary beverages, candies, and baked goods. Excessive ...

IL-2 and IL-15 receptor complexes share the β and γ chains ... recombinant IL-2 protein also enables the proliferation of mitogen-activated T cells and NK cells, the culture of IL-2 dependent ...

Liver diseases, both acute and chronic, continue to pose significant clinical challenges due to high morbidity and mortality ...

A family of proteinase-activated receptors (PARs ... whereas downregulation was achieved by inhibition of mitogen-activated protein kinase 1. PAR-2 activation induced production of ...

The most important takeaway from the study is that these data suggest that CD47 is an attractive target for drug development.

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

and galanin receptor 3 (GALR3), through pathways involving protein kinase C (PKC), mitogen-activated protein kinases (MAPKs), and Toll-like receptor 4 (TLR4). β-carotene, curcumin, tryptophan ...

Future Virology. 2013;8(11):1127-1134. Breast milk contains high concentration of secretory antibodies, mainly IgA, with a broad range of specificities reflecting both maternal immunologic memory ...