The principal therapeutic action of morphine is analgesia. The precise mechanism of action is not known but the effects are thought to be mediated through opioid-specific receptors located in the CNS.

The risk to develop PTSD was significantly reduced (p<0.001) when morphine had been administered. This interaction remained significant after controlling for severity and mechanism of injuries ...

Opioids have been an essential part of anesthesia, but they aren’t the only way to manage pain.

Although many dosing regimens for intravenous morphine have been studied, 0.10 mg/kg generally is recommended as an acceptable starting dose for treating patients with acute pain. Unfortunately ...

Nov. 18, 2024 — A promising daily tablet is effective at increasing height and improving proportional limb growth in children with achondroplasia, the most common form of dwarfism, according to ...

The public has shown support for assisted dying being legalised, in principle, but disability campaigners are concerned.

Collegium Pharmaceutical’s pain management portfolio, including Xtampza ER and Belbuca, drives 92.8% of revenues. Read why ...

Labour MP Kim Leadbeater has said the assisted dying bill is not about “choosing between life and death”, but rather giving people the autonomy to choose how and when they die. A historic five-hour ...

Patients with relapsed or refractory CD19-positive B-cell acute lymphoblastic leukemia (ALL) who were treated with the novel anti-CD19 chimeric antigen receptor (CAR) T cell therapy, obecabtagene ...

Engineered heme proteins exhibit excellent sustainable catalytic carbene transfer reactivities enabling the transformation of olefins to cyclopropanes, however, exploiting unactivated and electron ...