Liquid-like protein condensates are ubiquitous in cellular systems and play key roles in physiological processes, with the condensed phase harboring a distinctive chemical microenvironment.
There are processes in the human body that can suppress the growth and proliferation of cancer cells. These mechanisms, including those involving the tumor suppressor protein p53, are widely studied ...
Corresponding author Richard Kriwacki, PhD, St. Jude Department of Structural Biology, investigated how the tumor suppressor p14ARF undergoes phase separation with nucleophosmin in the nucleolus to ...
Did you know that every single living thing is made up of teeny, tiny unit structures? You have more than 75 trillion of them in your body – they’re called cells and they are amazing! Today we are ...
IN recent years striking discoveries have been made regarding the origin and history of the nucleolus. It has como to be recognized that in every cell of a plant or animal species there is at ...
Ribosomes themselves are assembled in a structure called the nucleolus, which is located inside the nucleus of the cell. And it is stress in this nucleolus that appears to significantly contribute to ...
The mechanisms underlying biological aging are becoming recognized as therapeutic targets to delay the onset of multiple age-related morbidities. Even greater health benefits can potentially be ...