In this study, our results uncover the function and mechanism of CHMP5 in the regulation of cell senescence and bone formation in osteogenic cells. Deletion of Chmp5 causes endolysosomal dysfunction ...

Studies have shown that inflammatory cell death leads to osteogenic cell pyroptosis and is the key to the development of osteoporosis. Various signals that induce inflammation in the body include ...

Department of Medical Life Sciences, Department of Medical Sciences (Graduate School), and Catholic Photomedicine Research Institute, College of Medicine, The Catholic University of Korea, 222 ...

It feels like the Splinter Cell remake has been on its way for a decent while now, which isn't helped by the fact it's been over two years since we heard anything official about the game.

You probably learned about organelles, those little “organs” inside cells that form compartments with individual functions. For example, mitochondria produce energy, lysosomes recycle waste ...

“This approach of utilizing metabolic modulation to improve MSC chondrogenic potential could be adapted into similar concepts for other therapeutic indications, such as osteogenic potential for bone ...

Stem cells are specialized cells that have the potential to develop into not one but many different types of cell. They are unlike any other cell for three specific reasons: They are unspecialized, ...

(2020). Investigation of multiphasic 3D-bioplotted scaffolds for site-specific chondrogenic and osteogenic differentiation of human adipose-derived stem cells for osteochondral tissue engineering ...

Mechanistically, biomechanical stretch stimulated S1P production by SphK1 in human valvular interstitial cells as measured by C17-S1P generation, whereas S1P/S1PR2 signaling induced their osteoblastic ...