In this study, our results uncover the function and mechanism of CHMP5 in the regulation of cell senescence and bone formation in osteogenic cells. Deletion of Chmp5 causes endolysosomal dysfunction ...

Studies have shown that inflammatory cell death leads to osteogenic cell pyroptosis and is the key to the development of osteoporosis. Various signals that induce inflammation in the body include ...

Department of Medical Life Sciences, Department of Medical Sciences (Graduate School), and Catholic Photomedicine Research Institute, College of Medicine, The Catholic University of Korea, 222 ...

You probably learned about organelles, those little “organs” inside cells that form compartments with individual functions. For example, mitochondria produce energy, lysosomes recycle waste ...

“This approach of utilizing metabolic modulation to improve MSC chondrogenic potential could be adapted into similar concepts for other therapeutic indications, such as osteogenic potential for bone ...

(2020). Investigation of multiphasic 3D-bioplotted scaffolds for site-specific chondrogenic and osteogenic differentiation of human adipose-derived stem cells for osteochondral tissue engineering ...

Detailed maps that pinpoint the positions of cells in tumours and probe the tumours’ biology are offering insights into the development of several cancers — including in the breast ...