Researchers identified a new receptor, neuropilin-1 (NRP1), which collaborates with a known receptor to regulate pain ...

Researchers at the NYU Pain Research Center have found a new receptor for nerve growth factor that plays an important role in ...

Another class of drugs that exploit a natural mechanism to decrease the ability of CaV2.2 to respond to pain signalling are the opioid drugs, like morphine and heroin. While very effective at ...

This knowledge can be used to develop drugs for chronic pain that are more effective and have fewer side effects. When the electrical signal reaches the end of one nerve cell, it is converted into ...

Another class of drugs that exploit a natural mechanism to decrease the ability of CaV2.2 to respond to pain signalling are the opioid drugs, like morphine and heroin. While very effective at ...

An illustration of the pain signaling pathway elicited by CGRP. CGRP activates the CGPR receptor on Schwann cells. The CGPR receptor traffics to endosomes, where sustained signaling results in the ...

Researchers are only just beginning to appreciate the complexity and diversity of the signaling systems used to relay nerve impulses for each type of pain (see "Why does it hurt?"). And these ...

Researchers at the NYU Pain Research Center have found a new receptor for nerve growth factor that plays an important role in pain signaling, even though it does not signal on its own, according ...

Common ivy is better known as a garden invader or a rather attractive indoor plant that's prone to triggering allergic ...

Macrophages have important roles in the induction and resolution of inflammation, but the intracellular pathways from inflammatory signals to pain response remain unclear. a recent study ...