The photobleaching technique FRAP (fluorescence recovery after photobleaching)) has been used since the mid-1970s to determine the diffusion constant of fluorescent antibody-labelled proteins on ...
Multi -epitope ligand cartography (MELC) is a technology using samples subjected to cycles of fluorescent staining, imaging and photobleaching. Each cycle can use an antibody for a different protein.
The technique exhibited enhanced photon collection efficiency and lower photobleaching rates compared to existing methods, maintaining 67% fluorescence intensity after 1,000 frames of imaging.
This study provides convincing evidence for functional subpopulations of β-cells responsible for Ca2+ signal initiation and maintenance using novel three-dimensional light sheet microscopy imaging and ...
This important study presents a statistical framework for the analysis of photometry signals and provides an open-source implementation. The evidence supporting the benefits of the presented ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. During PINK1- and Parkin-mediated mitophagy, ...