In “My Own Country,” a 1994 memoir, Dr. Abraham Verghese, an infectious disease physician, recounts the story of a young man ...

This interesting study presents valuable information on how human cytomegalovirus (HCMV) infection disrupts the activity of the TEAD1 transcription factor, leading to widespread chromatin alterations.

Investigators from Duke University hypothesized that hirudin-like protease inhibitors could be generated by linking exosite-binding aptamers with small-molecule active site inhibitors, thus generating ...

This useful study presents findings on how some antibiotics, which inhibit protein synthesis in bacteria, affect the translation in mitochondrial ribosomes. The authors provide solid evidence that ...

To access the webcast and subsequent archived recording of the presentation, please visit the “Presentations” section of the KALA website at About KALA BIO, Inc. KALA is a clinical-stage ...

Korro Bio has secured approvals in Australia to commence the Phase I/IIa trial of KRRO-110, aimed at treating AATD.

Analysts are estimating that Enanta Pharma will report an earnings per share (EPS) of $-1.16. The announcement from Enanta Pharma is eagerly anticipated, with investors seeking news of surpassing ...

The term “protease inhibitor” refers to a class of medications rather than to a single medication. Specifically, they are antiviral drugs. But unlike the many, more common antiviral drugs that ...

The natural anticoagulant hirudin achieves potent activity by inhibiting both thrombin’s exosite and active site. We hypothesize that hirudin-like protease inhibitors can be generated de novo by ...

HIV drug resistance can happen if the HIV virus in your body changes form, or mutates. This will affect how well your antiretroviral therapy (ART) works. Medications that are used to control your ...

Two additional M pro inhibitors, Ensitrelvir (ETV ... "Assessing the Inhibition Efficacy of Clinical Drugs Against the Main Proteases of SARS-CoV-2 Variants and Other Coronaviruses," provides ...