AMP-activated protein kinase (AMPK) is a cellular energy sensor that mediates multiple crucial metabolic pathways that may be an attractive therapeutic target in sepsis. Pre-clinical experimental ...

AlphaFold’s ability to accurately predict proteins’ 3D structures has been repeatedly described as a revolution for biochemistry, a sentiment echoed by the Nobel committee as it announced that Jumper ...

Targeted therapy revolutionized cancer treatment, with gene fusions leading the way when the FDA approved imatinib in 2001 to ...

P2Rank: Protein-ligand binding site prediction tool based on machine learning. Stand-alone command line program / Java library for predicting ligand binding pockets from protein structure.

A well-balanced diet always includes protein, no matter whether you prefer eating meat, tofu or another source. Protein is an essential part of what helps your body perform its most essential ...

Summary: Researchers have identified unique RNA structures called G-quadruplexes (G4s) that promote harmful α-synuclein protein aggregation linked to neurodegenerative diseases like Parkinson’s.

Mapping genetic variants to the 3D structure of proteins is typically a complex task, but this new portal significantly simplifies the process. The portal compiles the 3D structures of proteins ...