The Falke group is currently investigating the molecular mechanisms of on-off switching of components within the chemosensory array, especially the mechanisms by which transmembrane receptors bind ...

Researchers reveal that spermidine-mediated acetylhypusination of RIPK1 suppresses necroptosis and insulin resistance, ...

In the study, "Melatonin receptor 1A variants as genetic cause ... and mitogen-activated protein kinase pathways, which triggered osteoblast senescence and bone loss. The findings point to a ...

Novel macrocyclic heteroaryl derivatives acting as non-receptor tyrosine-protein kinase TYK2 and/or JAK1 and/or JAK2 inhibitors have been reported in a Hangzhou Highlightll Pharmaceutical Co. Ltd.

Two kinase inhibitors have been recommended by the European Medicines Agency for the treatment of non-small cell lung cancer.

This bioinformatics-assisted review describes key biological elements of known pathways, such as the forkhead box protein ...

Genistein boosts GnRH production via regulating kisspeptin receptors, sirtuin 1 (SIRT1), protein kinase c γ (PKCγ), and makorin ring finger protein 3 (MKRN3). DHA, PUFA, and SFA promote GnRH mRNA ...