The molecular basis of phospho-tyrosyl-regulation of Src-family and Syk-family protein tyrosine kinases in signaling pathways is a current focus of ... We are also actively investigating the ...

We rapidly developed a sequential model by which the TCR initiates signaling via interactions with tyrosine kinases 37. Coreceptor-associated Lck is brought into proximity of the TCR ITAMs during ...

“Signaling by Receptor Tyrosine Kinases” edited by Joseph Schlessinger and Mark A. Lemmon, Cold Spring Harbor Laboratory Press, ISBN978-1-936113-33-0, pages 287-303, (2014). Xu K, Tzvetkova-Robev D, ...

AKT signaling pathway is one of the most critical and extensively investigated signaling pathways. It is the central ...

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science ...

This work is an important contribution to understanding the role of FGF signaling in the induction of primitive-like cells in a 2D system of human gastrulation. The authors provide compelling evidence ...