These RNA ranks are simple structures stabilized by the formation of complementary base pairs ... To reach their conclusions, the team applied the technique of optical tweezer force spectroscopy, a ...

Lipid nanoparticles made from lipids optimized via directed chemical evolution show high performance as mRNA delivery vehicles.

Engineers have cooked up a new way to improve mRNA delivery, developing an optimal 'recipe' for ionizable lipids -- key ingredients in lipid nanoparticles (LNPs), the molecules behind the COVID-19 ...

Penn Engineers have cooked up a new way to improve mRNA delivery, developing an optimal “recipe” for ionizable lipids — key ...

Penn Engineers have cooked up a new way to improve mRNA delivery, developing an optimal "recipe" for ionizable lipids—key ...

The reason is simple: our research has shown that we can outperform the market by ... a clinical-stage biotechnology company.

The study, recently published in Nature Chemical Biology, presents an unexpected connection between spermidine ... Following the discovery of sirtuin-linked acylspermidines in the simple organism C.

Led by Michael J. Mitchell, Associate Professor in Bioengineering, the researchers refined this delivery process by optimizing the structure of ionizable lipids. Moving beyond existing methods limited ...

For more than four decades, scientists have noticed a mysterious chemical in the treated drinking water of millions of people ...