“Our approach mimics the natural, non-antigenic mechanism of TCR activation, much akin to bacterial superantigen-induced TCR activation.” Activation via TCR Vβ solves the current IO ...

Staphylococcus aureus pathogenicity islands (SaPIs) are highly mobile phage-related mobile genetic elements in staphylococci. Elements similar to SaPIs have been detected in related Gram-positive ...

It is a serious and potentially life-threatening condition caused mostly by superantigen producing Staphylococcus aureus. They present with high grade fever, rashes, hypotension, desquamation ...

[68,69] Doxycycline (a tetracycline) was shown to inhibit superantigen-induced T-cell proliferation and cytokine and chemokine production by PMN cells in vitro. [70] Therefore, these antibiotics ...

A: Animal; ACE: Accessory cholera enterotoxin; H: Human; ZOT: Zonula occludens toxin.