The company will develop a pipeline of small molecule inhibitors that target a unique lipid-binding pocket on proteins.

The .AI extension, primarily the country code top-level domain for Anguilla, has gained prominence among those in the artificial intelligence sector. 101domain has responded to this trend by offering ...

CREATE DOMAIN creates a new domain. A domain is essentially a data type with optional constraints (restrictions on the allowed set of values). The user who defines a domain becomes its owner. If a ...

Baobab Aibio Co. Ltd. has disclosed transcriptional coactivator YAP1/transcriptional enhancer factor (TEAD) interaction inhibitors reported to be useful for the treatment of cancer.

We observe that the AP-1 family of TFs (Fos/Jun) are frequently required for binding of TEAD TFs and for enhancer function. However, many sequence variants outside of core motifs for AP-1 and TEAD ...

YAP and TAZ directly interact with JUNB and STAT3 via a WW domain important for transformation, and they stimulate transcriptional activation by AP-1 proteins. JUNB, STAT3, and TEAD co-localize at ...

Google Argentina's domain name was bought by a web designer while the site was out of action for two hours in the country last Wednesday. Nicolas Kurona, aged 30, said he managed to buy Google.com ...

By using three broad types of measurements—working capital, asset performance, and capital structure—you may evaluate the strength of a company's balance sheet and, thus, its investment quality.