The safety and overall survival seen in the ARC-10 trial lends further support to the firm's strategy of pairing domvanalimab and zimberelimab with chemo in STAR-121.

Novartis, meanwhile, handed rights to TIGIT antibody ociperlimab to BeiGene a year ago, two years after paying $300 million upfront for an option on the drug. Like PD-1/PD-L1, TIGIT is thought to ...

GSK and iTeos anti-TIGIT antibody belrestotug showed efficacy in a phase 2 trial in PD-L1-positive non-small cell lung cancer (NSCLC), providing some much-needed positive news for the beleaguered ...

PD-L1 表达情况是目前临床上应用最广泛的免疫治疗生物标志物之一。一系列临床研究结果证实肿瘤细胞和/或肿瘤相关免疫细胞 ...

The first patients have been dosed in three global, randomized phase 3 trials evaluating the efficacy and safety of ...

Vibostolimab是默沙东开发的一款抗TIGIT单抗，可通过阻断TIGIT ... 阿维鲁单抗是默克开发的一款PD-L1单抗，于2017年3月首次在美国获批上市。

Three phase 3 trials of combinations including datopotamab deruxtecan for the treatment of non–small cell lung cancer are beginning.

The company’s most advanced asset is dom, an Fc-silent anti-TIGIT monoclonal antibody that ... being investigated for the treatment of all PD-L1 subgroups of 1L NSCLC. The Phase 3 trial (STAR ...

This study is a randomized, open-label, three-arm study evaluating domvanalimab, an Fc-silent anti-TIGIT monoclonal antibody ... or non-squamous NSCLC with a PD-L1 tumor proportion score of ...

Data, including overall survival, from ARC-10, a randomized study evaluating domvanalimab plus zimberelimab in front-line, PD-L1-high ... for the Fc-silent anti-TIGIT antibody domvanalimab ...

This study is a randomized, open-label, three-arm study evaluating domvanalimab, an Fc-silent anti-TIGIT monoclonal antibody, plus zimberelimab, an anti-PD-1 monoclonal antibody, versus zimberelimab ...

Clinical Data shows that Q-1802 has significant anti-tumor activity. Q-1802, a humanized bispecific antibody, is the first FDA-approved and the first enter clinical trial Claudin18.2/PD-L1 bispecific ...