Remarkably, all the various types of SMC proteins from humans and yeast add the same amount of twist—they turn DNA 0.6 times at every DNA loop extrusion step. This shows that the DNA extrusion ...

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Strikingly, all the various types of SMC proteins from human and yeast add the same amount of twist -- they turn DNA 0.6 times at every at every DNA loop extrusion step. This shows that the DNA ...

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A new study reveals that SMC proteins not only loop DNA but also twist it, a process conserved across different organisms. This finding is key to understanding DNA organization and its impact on gene ...

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Intriguingly, all SMC proteins from both humans and yeast impart an identical twist—0.6 turns during each step of DNA loop extrusion. This shows that the DNA extrusion and twisting mechanisms stayed ...