The EMBO Journal3d
Acetylation of TIR domains in the TLR4-Mal-MyD88 complex regulates immune responses in sepsis
Activation of macrophage TLR4 by bacterial endotoxins is important for the progression of sepsis, but the underlying ...
MDA Kickstart Program Launches for Ultra-Rare Neuromuscular Disease Drug Development
Collaboration with UC Davis, Manufacturing Partnership with Forge Biologics MDA Kickstart Muscular Dystrophy Association ...
Cell Reports | 华中农业大学周道绣/赵毓团队揭示赖氨酸去乙酰化酶调控水稻耐热性的机制
蛋白质乙酰化 作为一种重要的蛋白质翻译后修饰参与多种生理过程，因此在植物生长发育及环境适应中发挥着重要调控作用。蛋白质乙酰化修饰机制和生物学功能的解析可为作物育种及改良提供新的思路和方法。
The EMBO Journal10d
Trained immunity of intestinal tuft cells during infancy enhances host defense against enteroviral infections in mice
Our present study implies that intestinal tuft cells can be trained by IL-25 and it may explain the different susceptibility ...
precisionmedicineonline11d
Muscular Dystrophy Association Announces First Project Under Kickstart Program
The first project in this program to advance gene therapies for very rare conditions will focus on CHAT-mutated congenital myasthenic syndrome.
Future Market Insights9d
Global Luciferase Assay Market Poised for Robust Growth, Projected to Reach USD 3,022.90 Million by 2034
The global luciferase assay market is experiencing impressive growth, with forecasts projecting its valuation to climb from USD 1,536.70 million in 2024 to USD 3,022.90 million by 2034. This ...
eLife6d
Pathogenic LRRK2 causes age-dependent and region-specific deficits in ciliation, innervation and viability of cholinergic neurons
Pathogenic activating point mutations in the LRRK2 kinase cause autosomal-dominant familial Parkinsońs disease (PD). In cultured cells, mutant LRRK2 causes a deficit in de novo cilia formation and ...