Researchers at the ICR co-led a recent study showing that it is possible to reverse drug resistance and slow tumour progression in prostate cancer by targeting myeloid white blood cells. Tumours can ...
This work will be of high interest to a broad swathe of scientists studying native macromolecules present at low concentrations in cells. Cryo-EM single-particle analyses typically require target ...
CryoDRGN has proven a powerful deep learning method for heterogeneity analysis in single particle cryo-EM. In particular, the method models a continuous distribution ... heterogeneity from datasets in ...
It usually has a different conformation in each cryo-EM image. "When you try to average all these images to determine the receptor's precise structure, you tend to end up with only a blur," Huang ...